Table 1.
Hormone effects on insulin sensitivity, oxidative stress, inflammation and endothelial function.
Insulin Sensitivity | Oxidative Stress | Inflammatory response | Endothelial cell function | |
Insulin | NA | ↓ [12] | ? | ↑ [12] |
Angiotensin 2 | ↓ [45] | ↑ [44] | ↑ [46] | ↓ [49] |
Aldosterone | ↓ [52] | ↑ [53] | ↑ [53] | ↓ [54] |
Epinephrine | ↓ [28] | ↑ [37] | ↑ [38] | ? |
Norepinephrine | ↓ [28] | ↑ [37] | ↑ [39] | ? |
Endothelin 1 | ↓ [62] | ↑ [59], [60] | ↑ [61] | ↓ [58] |
Leptin | ↓ [22] | ↑ [20] | ↓ [21] | ↓ [20] |
Consequences of hormone actions on oxidative stress, inflammatory responses, and endothelial-cell dysfunction were summarized from published evidence. Arrows indicate the direction of hormone-mediated changes, question marks indicate unknown effects.