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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Pharm Res. 2014 Feb 22;31(7):1644–1655. doi: 10.1007/s11095-013-1267-1

Table III.

Cardiac CBR1, CBR3, AKR1A1, AKR1C3, and AKR7A2 protein expression in samples from donors without- and with- DS

Non-DS DS
Transcript nmol/g cytosolic protein nmol/g cytosolic protein P value
Mean ± SD Range Mean ± SD Range
CBR1 11.9 ± 8.9 1.2 – 30.2 18.8 ± 6.7 14.3 – 31.1 0.04
CBR3 6.3 ± 5.5 1.0 – 15.8 2.3 N/A N/A
AKR1A1 27.4 ± 17.3 0.0 – 74.1 28.3 ± 15.4 15.0 – 63.0 0.86
AKR1C3 26.0 ± 22.4 0.5 – 70.3 18.4 ± 23.2 0.3 – 61.4 0.32
AKR7A2 31.0 ± 21.0 5.4 – 68.1 33.8 ± 19.6 6.8 – 61.2 0.97

N/A., not applicable (n = 1)