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Cardiac CBR1 mRNA expression, CBR1 protein expression and daunorubicin reductase activity in hearts from donors with- DS stratified by CBR1 rs9024 genotype status
| CBR1 rs9024 genotype (n) |
CBR1 mRNA copy number ratio Mean ± SD |
CBR1 protein (nmol/g cytosolic protein) Mean ± SD |
Daunorubicin reductase activity (nmol daunol/mg. min) Mean ± SD |
|---|---|---|---|
| AA (2) | 36423.3 ± 38775.3 | 18.8 ± 4.7 | 1.5 ± 0.9 |
| AG (6) | 59954.5 ± 9322.3 | 31.1 | 4.5 ± 1.9 |
| GG (21) | 11138.5 ± 47942.6 | 14.7 ± 0.7 | 1.1 ± 0.2 |
