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. 2014 Apr 7;4(6):1081–1089. doi: 10.1534/g3.114.010819

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Copyright © 2014 Felton and Johnson

This is an open-access article distributed under the terms of the Creative Commons Attribution Unported License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The hlh-17 animals respond selectively to reuptake inhibitors. (A) Pretreatment with the DAT reuptake inhibitor, bupropion, increases the SWIP phenotype of N2, hlh-17(ns204), dat-1(ok157), and hlh-17(ns204); dop-3(vs106) animals. The ability of bupropion to enhance SWIP behavior is not dependent on DOP-3. The SWIP phenotype in hlh-17(ns204) animals is unaffected by pretreatment with reserpine (B) or fluoxetine (C). In all panels, n = 30 animals/rep/strain; dark bars = minus inhibitor; and light bars = plus inhibitor. *P < 0.05; **P < 0.005; ***P < 0.0005.