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CZT-1 is involved in ROS accumulation. (A and B) ROS accumulation was assessed with dihydrorhodamine 123 by staining cells grown in liquid minimal medium for 4 hr and treated with staurosporine (STS) or DMSO for 30 min. Representative flow cytometry histograms are shown in (A) (solid line, STS; shaded, DMSO) and the respective quantification is shown in (B). *P-value <0.05.
