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Pathways that were statistically overrepresented among genes. (A) Upregulated at 36 hpi, (B) upregulated at 48 hpi, (C) downregulated at 36 hpi, and (D) downregulated at 48 hpi in MIMs isolated from S. uberis–infected animals. Upregulated genes were significantly enriched for roles in inflammatory and other innate immune pathways, whereas downregulated genes were significantly associated with metabolic pathways.
