Table 3.
Insulin dose and dosing frequency at baseline and Week 24 by baseline BMI
| Baseline BMI group (kg/m2) | ||||
|---|---|---|---|---|
| <25.0 | 25.0 to <30.0 | 30.0 to <35.0 | ≥35.0 | |
| Insulin dose (U/day) | ||||
| n | 3,045 | 4,186 | 2,365 | 1,054 |
| Baselinea | 15.8 ± 7.8 | 18.1 ± 9.7 | 18.9 ± 10.8 | 20.8 ± 12.8 |
| Week 24a | 21.8 ± 11.4 | 25.9 ± 14.2 | 29.9 ± 15.6 | 34.8 ± 18.9 |
| Insulin dose (U/kg) | ||||
| n | 3,045 | 4,186 | 2,365 | 1,054 |
| Baselinea | 0.27 ± 0.13 | 0.25 ± 0.13 | 0.22 ± 0.12 | 0.20 ± 0.12 |
| Week 24a | 0.36 ± 0.18 | 0.35 ± 0.19 | 0.35 ± 0.18 | 0.35 ± 0.18 |
| Dosing frequency at baseline, n (%) | ||||
| n | 3,045 | 4,186 | 2,365 | 1,054 |
| Once dailyb | 2,815 (92.4) | 3,687 (88.1) | 2,205 (93.2) | 962 (91.3) |
| Twice dailyb | 222 (7.3) | 492 (11.8) | 157 (6.6) | 91 (8.6) |
| Thrice dailyb | 7 (0.2) | 6 (0.1) | 3 (0.1) | 1 (0.1) |
| >Thrice dailyb | 1 (0.0) | 1 (0.0) | – | – |
| Dosing frequency at Week 24, n (%) | ||||
| n | 2,580 | 3,691 | 2,176 | 968 |
| Once dailyb | 2,160 (83.7) | 2,841 (77.0) | 1,705 (78.4) | 733 (75.7) |
| Twice dailyb | 337 (13.1) | 729 (19.8) | 383 (17.6) | 180 (18.6) |
| Thrice dailyb | 28 (1.1) | 35 (0.9) | 37 (1.7) | 23 (2.4) |
| >Thrice dailyb | 55 (2.1) | 86 (2.3) | 51 (2.3) | 32 (3.3) |
The mean total daily IDet dose at baseline and Week 24 is presented in units of U/day and U/kg for each group. Dosing frequency of IDet at baseline and Week 24 is summarized and presented as once daily, twice daily, thrice daily and >thrice daily. As this was a non-interventional study, data collection was based on the number of patients that reported dose details at baseline and Week 24
BMI body mass index
aData are represented as mean ± SD
bData are represented as n (%)