Table 3.

Logistic regression—predictors of early discontinuation

	Odds ratio	95% confidence interval		P value
		Lower	Upper
Patient characteristics
Age	0.99	0.99	0.99	<0.001
Femalea	1.13	1.09	1.16	<0.001
Northeastb	0.75	0.72	0.78	<0.001
North Centralb	0.84	0.81	0.87	<0.001
Westb	0.91	0.87	0.95	<0.001
Health maintenance organizationc	1.12	1.07	1.17	<0.001
Point of servicec	1.05	0.99	1.11	0.095
Other health insurancec	0.97	0.91	1.02	0.239
Pre-period
Charlson comorbidity index	1.01	1.00	1.02	0.121
Hospitalized	1.01	0.96	1.06	0.758
Emergency room visit	1.08	1.04	1.13	<0.001
Total costs	1.01	1.00	1.01	<0.001
Microvascular complication	1.03	0.97	1.09	0.367
Macrovascular complication	0.99	0.94	1.03	0.507
Depression	1.10	1.01	1.20	0.029
Obesity	0.92	0.87	0.98	0.006
Dementia	1.52	0.83	2.80	0.179
Alcohol use disorder	0.97	0.82	1.15	0.753
Mental health disorder	1.05	1.00	1.10	0.071
Use of oral antidiabetic medication	1.13	1.08	1.18	<0.001
Number of antidiabetic medications classes	0.92	0.90	0.93	<0.001
Number of classes of all-cause medications	0.99	0.98	0.99	<0.001
Use of antidepressant	0.84	0.80	0.87	<0.001
Use of other mental health medications	1.04	1.00	1.09	0.060
Index prescription
Analogd	0.78	0.74	0.83	<0.001
Viale	0.73	0.71	0.75	<0.001
Mixturef	0.74	0.70	0.78	<0.001
Copayment	1.00	1.00	1.00	0.187

Reference categories: ^amale, ^bSouth, ^cpreferred provider organization, ^dhuman insulin, ^epen, ^fbasal insulin