Table 4.
Ocular toxicities
| Patient ID | AE (Preferred term) | Study day of onset | Duration (Days) | Severity | Relation to SGN-40 |
|---|---|---|---|---|---|
| 029-0010 |
Eye pain |
1 |
4 |
Grade 1 |
Possibly |
| Eye pain |
5 |
3 |
Grade 1 |
Possibly |
|
| Eye pain |
8 |
4 |
Grade 1 |
Possibly |
|
| 029-0011 |
Eye irritation |
1 |
1 |
Grade 1 |
Possibly |
| Vision blurred |
8 |
1 |
Grade 1 |
Possibly |
|
| 044-0001 |
Conjunctivitis |
5 |
14 |
Grade 2 |
Probably |
| Eye pain |
11 |
11 |
Grade 2 |
Possibly |
|
| Eye infection |
16 |
4 |
Grade 2 |
Unlikely |
|
| Orbital cellulitis (SAE) |
18 |
4 |
Grade 3 |
Possibly |
|
| 059-0001 |
Dry eye |
16 |
8 |
Grade 2 |
Possibly |
| 066-0010 |
Conjunctival irritation |
16 |
22 |
Grade 1 |
Possibly |
| Eye pain |
37 |
36 |
Grade 1 |
Possibly |
|
| 066-0011 |
Conjunctival hyperaemia |
4 |
11 |
Grade 2 |
Possibly |
| 066-0005 |
Conjunctival hyperaemia |
1 |
56 |
Grade 1 |
Unrelated |
| 005-0002 | Conjunctival hemorrhage | 17 | 1 | Grade 3 | Unrelated |