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The N-terminus of Kinesin-13 is a primary determinant of kinesin localization. (A) Schematic diagram showing the Kinesin-13 domains and their percentage similarity with respect to Kif2c/MCAK. (B) Images of HeLa cells transiently expressing GFP fusions to full length and domains of Kif2a, Kif2b, and Kif2c. The ΔN and ΔMC domains represent GFP-fusions lacking the N-terminus or the motor and C-terminal domains of the kinesins, respectively. Adapted from Welburn and Cheeseman [2012].
