Table 1.
Genes with changes in expression (unadjusted P < 0.01) from the microarray
| Gene Name | Ensembl ID | Proportional change | P-value | Adjusted P-value |
|---|---|---|---|---|
| PTPRQ | ENSMUSG00000035916 | −1.668142552 | 1.22E-05 | 0.258653553 |
| RPRM | ENSMUSG00000075334 | −1.42558442 | 0.000255653 | 0.999832538 |
| ENPP2 | ENSMUSG00000022425 | −1.170514788 | 0.001266519 | 0.999832538 |
| PAQR9 | ENSMUSG00000064225 | −1.234515233 | 0.001500896 | 0.999832538 |
| SCARA3 | ENSMUSG00000034463 | −1.146440488 | 0.001698927 | 0.999832538 |
| LRPPRC | ENSMUSG00000024120 | −1.149490043 | 0.001915957 | 0.999832538 |
| GM1027 | ENSMUSG00000047502 | −1.132141912 | 0.002083288 | 0.999832538 |
| FRY | ENSMUSG00000056602 | −1.316716103 | 0.002264682 | 0.999832538 |
| TUBA1A | ENSMUSG00000072235 | −1.158236745 | 0.002350494 | 0.999832538 |
| REEP6 | ENSMUSG00000035504 | −1.287813751 | 0.002673204 | 0.999832538 |
| 6330409N04RIK | ENSMUSG00000021930 | −1.154864691 | 0.00278719 | 0.999832538 |
| GRXCR1 | ENSMUSG00000068082 | −1.374271986 | 0.003023447 | 0.999832538 |
| HAUS1 | ENSMUSG00000041840 | −1.460383181 | 0.00302821 | 0.999832538 |
| CXADR | ENSMUSG00000022865 | −1.177070915 | 0.003301987 | 0.999832538 |
| CALB2 | ENSMUSG00000003657 | −1.872545244 | 0.003340481 | 0.999832538 |
| HS6ST2 | ENSMUSG00000062184 | −1.197160378 | 0.003409697 | 0.999832538 |
| HSD17B7 | ENSMUSG00000026675 | −1.508593767 | 0.003609971 | 0.999832538 |
| TCEA3 | ENSMUSG00000001604 | 1.145237128 | 0.003669075 | 0.999832538 |
| CYLD | ENSMUSG00000036712 | −1.221211996 | 0.003802919 | 0.999832538 |
| FAM177a | ENSMUSG00000095595 | −1.298189092 | 0.003856988 | 0.999832538 |
| GHSR | ENSMUSG00000051136 | −1.133219164 | 0.003930565 | 0.999832538 |
| MYCL1 | ENSMUSG00000028654 | −1.455969357 | 0.005057643 | 0.999832538 |
| CXADR | ENSMUSG00000022865 | −1.194386586 | 0.005408051 | 0.999832538 |
| HSPA2 | ENSMUSG00000059970 | −1.32492769 | 0.005413211 | 0.999832538 |
| ACCN2 | ENSMUSG00000023017 | −1.223432756 | 0.005542887 | 0.999832538 |
| CYLD | ENSMUSG00000036712 | −1.163235475 | 0.005846245 | 0.999832538 |
| ASAP2 | ENSMUSG00000052632 | 1.119392959 | 0.006286889 | 0.999832538 |
| ANO1 | ENSMUSG00000031075 | −1.408344537 | 0.006989795 | 0.999832538 |
| SLC25A5 | ENSMUSG00000016319 | −1.108047476 | 0.007157786 | 0.999832538 |
| MARVELD3 | ENSMUSG00000001672 | −1.243287418 | 0.007360472 | 0.999832538 |
| 6030405A18Rik | ENSMUSG00000056306 | −1.366002261 | 0.007580547 | 0.999832538 |
| TMEM25 | ENSMUSG00000002032 | −2.539909188 | 0.007733011 | 0.999832538 |
| C030014I23RIK | ENSMUSG00000060380 | −1.291455753 | 0.0077525 | 0.999832538 |
| NFE2L3 | ENSMUSG00000029832 | −1.251621116 | 0.007866223 | 0.999832538 |
| KCTD3 | ENSMUSG00000026608 | −1.101026278 | 0.008013213 | 0.999832538 |
| AFTPH | ENSMUSG00000049659 | −1.153614005 | 0.008310229 | 0.999832538 |
| KIF2A | ENSMUSG00000021693 | −1.131059659 | 0.008322974 | 0.999832538 |
| PRKCDBP | ENSMUSG00000037060 | 1.181724169 | 0.008391717 | 0.999832538 |
| 2810011L19RIK | ENSMUSG00000097929 | −1.639169358 | 0.008672408 | 0.999832538 |
| ANGPTL2 | ENSMUSG00000004105 | 1.173678608 | 0.008928208 | 0.999832538 |
| C030014I23RIK | ENSMUSG00000060380 | −1.296314718 | 0.008978949 | 0.999832538 |
| CHRNA1 | ENSMUSG00000027107 | −1.689431657 | 0.009032761 | 0.999832538 |
| SEMA3E | ENSMUSG00000063531 | −1.288802355 | 0.009075836 | 0.999832538 |
| ERLIN2 | ENSMUSG00000031483 | −1.137591058 | 0.009078345 | 0.999832538 |
| OTOF | ENSMUSG00000062372 | −1.822630656 | 0.009080105 | 0.999832538 |
| HDAC2 | ENSMUSG00000019777 | −1.155381566 | 0.009307828 | 0.999832538 |
| KCTD14 | ENSMUSG00000051727 | 1.133454846 | 0.00948616 | 0.999832538 |
| LRRC24 | ENSMUSG00000033707 | −1.173728732 | 0.009519745 | 0.999832538 |
| TLN2 | ENSMUSG00000052698 | 1.151209002 | 0.00963685 | 0.999832538 |
| CHRNA9 | ENSMUSG00000029205 | −1.462315299 | 0.009711404 | 0.999832538 |
List of genes from the microarray with differences in expression between Pprq-CAT-KO homozygotes and wildtype littermates (unadjusted P < 0.01). Four genes are known to be involved in deafness (PTPRQ, OTOF, GRXCR1 and CHRNA9).