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. 2014 May 12;14:214. doi: 10.1186/1472-6963-14-214

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Copyright © 2014 Martínez-González et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effects of physician-nurse substitution on mortality in A) all trials and by B) subgroups. Legend. CI, confidence interval; df, degrees of freedom; N, number of patients with events; Total, total number of patients per group; RR, Relative Risk; Chi², statistical test for heterogeneity; P, p-value of Chi² (evidence of heterogeneity of intervention effects); I², amount of heterogeneity between trials; Overall P, p-value for significance of effects of interventions; NLC, Nurse-Led Care; PLC, Physician-Led Care; NP, Nurse Practitioner; NP+, Nurse Practitioner with higher degree/courses/specialisation; RN, Registered Nurse. ^*Andryukhin et al. (2010) [46] reported data at 6 and 18 months and was incorporated accordingly.