Table 3.
Univariate comparisons of baseline variables in those below & above median number of non-serious adverse events (NSAEs)
| Variable | NSAE ≤ 4 (N 313) |
NSAE > 4 (N 327) |
t | P | ||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| CFS symptom count | 4.4 | 1.8 | 4.9 | 1.8 | 3.87 | < .001 |
| PHQ-15 | 13.5 | 4.3 | 14.8 | 4.8 | 3.63 | < .001 |
| BMI | 25.0 | 4.8 | 25.9 | 5.1 | 2.40 | .02 |
| SF36 PF | 39.6 | 15.2 | 36.5 | 16.2 | 2.48 | .01 |
| CBRQ embarrassment | 11.6 | 5.5 | 12.6 | 5.5 | 2.33 | .02 |
| Fatigue | 27.8 | 3.7 | 28.5 | 3.8 | 2.15 | .03 |
| HADS depression | 8.0 | 3.6 | 8.6 | 3.9 | 2.14 | .03 |
| HADS anxiety | 7.7 | 4.2 | 8.3 | 4.3 | 1.80 | .07 |
| CBRQ all or nothing | 13.6 | 3.8 | 14.1 | 3.8 | 1.57 | .12 |
| CBRQ catastrophising | 7.6 | 3.4 | 8.0 | 3.3 | 1.54 | .12 |
| WSAS | 26.9 | 6.3 | 27.6 | 6.3 | 1.39 | .16 |
| Jenkins sleep | 11.9 | 4.8 | 12.4 | 4.8 | 1.23 | .22 |
| Self-efficacy | 4.8 | 1.5 | 4.7 | 1.6 | 0.86 | .39 |
| CBRQ behaviour avoidance | 18.8 | 4.9 | 19.2 | 5.2 | 0.56 | .58 |
| CBRQ symptom focusing | 12.8 | 4.9 | 13.0 | 5.0 | 0.51 | .61 |
| CBRQ fear avoidance | 15.2 | 4.0 | 15.1 | 3.9 | 0.19 | .85 |
| CBRQ damage | 11.0 | 3.4 | 11.0 | 3.3 | 0.025 | .98 |
CFS = chronic fatigue syndrome, PHQ = Patient Health Questionnaire, BMI = body mass index, SF36 PF = short form 36 item physical function, HADS = Hospital Anxiety Depression Scale, CBRQ = Cognitive Behavioural Responses Questionnaire, WSAS = Work and Social Adjustment Scale.