Table 4.
Association of baseline diagnoses with number of NSAEs below and above median N (%)
| NSAE ≤ 4 | NSAE > 4 | X2 | P | |||
|---|---|---|---|---|---|---|
| Total | 313 | 49% | 327 | 51% | ||
| London ME case | ||||||
| Met (329) | 177 | 56 | 152 | 46 | 6.49 | .011 |
| Not met (311) | 136 | 44 | 175 | 54 | ||
| All psychiatric diagnoses | ||||||
| Present (299) | 128 | 41 | 171 | 52 | 8.35 | .004 |
| None (341) | 185 | 59 | 156 | 48 | ||
| All depressive disorders | ||||||
| Present (213) | 85 | 27 | 128 | 39 | 10.35 | .001 |
| None (427) | 228 | 73 | 199 | 61 | ||
| Major depressive disorder | ||||||
| Present (112) | 44 | 14 | 68 | 21 | 5.03 | .025 |
| None (528) | 269 | 86 | 259 | 79 | ||
| Minor depressive disorder | ||||||
| Present (67) | 28 | 9 | 39 | 12 | 1.52 | .220 |
| None (573) | 285 | 91 | 288 | 88 | ||
| Dysthymic disorder | ||||||
| Present (71) | 24 | 8 | 47 | 14 | 7.29 | .007 |
| None (569) | 289 | 92 | 280 | 86 | ||
| All anxiety disorders | ||||||
| Present (202) | 92 | 29 | 110 | 34 | 1.33 | .250 |
| None (438) | 221 | 71 | 217 | 66 | ||
| Generalised anxiety disorder | ||||||
| Present (132) | 56 | 18 | 76 | 23 | 2.80 | .094 |
| None (508) | 257 | 82 | 251 | 77 | ||
| Fibromyalgia | ||||||
| Present (138) | 69 | 22 | 69 | 21 | 0.07 | .79 |
| None (501) | 244 | 78 | 257 | 79 | ||
| SAEs or SARs during follow-up | ||||||
| Present (51) | 20 | 6 | 31 | 9 | 2.08 | .15 |
| None (589) | 293 | 94 | 296 | 91 | ||
All depressive disorders included major and minor depressive disorders and dysthymia. All anxiety disorders included generalised anxiety disorder, panic disorders, phobias and post-traumatic stress disorders. SAEs + SARs = number of participants with one or more serious adverse events or reactions.