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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: J Neurochem. 2014 Mar 27;130(1):41–49. doi: 10.1111/jnc.12710

Fig. 5.

Fig. 5

KCa3.1 gene knockout inhibits TGF-β-induced GFAP and CSPG protein expression. (A) The absence of KCa3.1 expression in astrocytes of KCa3.1−/− mice was confirmed by Western blot. (B-C) Astrocytes from KCa3.1−/− mice prevented the TGF-β-induced increase in GFAP (p < 0.05, C) and CSPG conditioned medium (CM) (p < 0.05, B) and CSPG lysates (LY) (p < 0.001, C) protein expression responses to TGF-β compared with astrocytes from WT mice (n = 3-4). * p < 0.05, *** p < 0.05 versus WT. WT: wild type, KO: knockout, Con: control.