Table 1.

Score for clinical parameters (on a scale from 0 to 3, maximum total score 87) in dogs with CanL.

Clinical sign	0	1	2	3
Appetite	Normal	Slight decrease	Moderate decrease	Anorexia
Mentation	Normal	Slight depression	Depression	Prostration
Exercise intolerance	No	Slight	Moderate	Refusal to move
Weight loss	No	Slight	Moderate	Severe
Polyuria	No	Slight	Moderate	Severe
Polydipsia	No	Slight	Moderate	Severe
UP/UC	No	<1	>1 < 2	>2
Localized muscle atrophy (temporal muscles)	No	Slight	Moderate	Severe
Generalized muscle atrophy	No	Slight	Moderate	Severe
Lymphadenomegaly	No	1-2 nodes	>2 < 4 nodes	Generalized
Splenomegaly	No		Yes
Conjunctivitis and/or blepharitis	No	Unilateral and slight	Bilateral or unilateral severe	Bilateral and severe
Uveitis and/or keratitis	No	Unilateral and slight	Bilateral or unilateral severe	Bilateral and severe
Pale mucous membranes	No	Slight	Moderate	Severe
Epistaxis	Never presented	Sporadic	Frequent	Persistent
Mouth ulcers or nodules	No	1 or 2 small ulcers or nodules	>2 small ulcers or nodules	>1/4 of oral cavity covered by ulcers or nodules
Vomiting	No	Sporadic	Frequent	Frequent with blood
Diarrhea	No	Sporadic	Frequent	Persistent
Lameness	No	Sporadic	Frequent	Constant
Erythema	No	<10% body surface or slight generalized erythema	10–25% body surface or moderate generalized erythema	>25% body surface
Dry exfoliative dermatitis	No	<10% body surface or slight generalized erythema	10–25% body surface or moderate generalized erythema	>25% body surface
Ulcerative dermatitis	No	1-2 ulcers	3–5 ulcers	>5 ulcers
Nodular dermatitis	No	1-2 nodules	3–5 nodules	>5 nodules
Sterile pustular dermatitis	No	1-2 pustules	3–5 pustules	>5 pustules
Alopecia	No	<10% body surface	10–25% body surface erythema	>25% body surface
Altered pigmentation	No	Localized	Multifocal	Generalized
Hyperkeratosis truffle and pads	No	Slight	Moderate	Severe
Generalized hyperkeratosis	No	Slight	Moderate	Severe
Onychogryphosis	No	Slight	Moderate	Severe