Table 3. Adjusted hazard ratio* for recurrent cardiac events† in LQTS females comparing oral contraceptive use to no oral contraceptive use during follow-up.
Parameter | Hazard ratio | (95% CI) | p-value |
---|---|---|---|
Time-dependent oral contraceptive use | 1.01 | 0.71– 1.44 | 0.95 |
Time-dependent β-blockers use | 0.36 | 0.24-0.54 | <0.0001 |
Abbreviations: CI denotes confidence interval
Adjusted for time-dependent β-blockers use, cardiac events prior to menarche, QTc interval, age at menarche, number of births, LQTS genotypes. See Methods for details.
Total recurrent cardiac events, in the 174 patients studied, including syncope or aborted cardiac arrest = 268.