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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: J Am Soc Echocardiogr. 2014 Apr 26;27(7):786–793.e2. doi: 10.1016/j.echo.2014.03.013

Figure 5.

Figure 5

Myocardial Ischemic Memory Imaging. (A) Mean (±SEM) background-subtracted acoustic intensity from MB-YSPSL in ischemic and remote territories in animals undergoing ischemia-reperfusion; and in the anterior wall in non-ischemic control animals. *p<0.05 vs remote territory and non-ischemic control; †p<0.05 vs non-ischemic control. (B) Examples of MCE images from an apical 4-chamber view from a single animal illustrate: an anterior and lateral wall perfusion defect (arrows) during LAD occlusion (top left); complete resolution of hypoperfusion 10 min after reflow (top right); color-coded images demonstrating signal enhancement from MB-YSPSL 30 min after reflow in ischemic (bottom left) and corresponding time point in non-ischemic (bottom right) primates after digital subtraction of the signal from freely circulating agent.