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Overexpression of calbindin prevents STS-induced intracellular calcium ([Ca2+]i) surge. (A) Fura-2 staining of MN9D/Neo cells treated with vehicle alone (Cont), 1 µM STS or STS in the presence of 40 µM of the calcium chelator BAPTA. Scale bar, 100 µm. (B) Quantitation of [Ca2+]i in MN9D/Neo cells treated with vehicle, STS, or STS in combination with BAPTA. NM9D/Calbindin cells were treated with STS and [Ca2+]i was compared. *p<0.05.
