Table 5.
Performance comparison of different feature sets with lasso-based feature selection in AD vs. MCI classification
| AD vs. MCI | |||
|---|---|---|---|
| LLF | SAEF | LLF + SAEF | |
| Supervised | |||
| MRI | 0.617 ± 0.020 | 0.631 ± 0.023 | 0.704 ± 0.026 |
| PET | 0.667 ± 0.023 | 0.645 ± 0.015 | 0.711 ± 0.025 |
| CSF | 0.659 ± 0.004 | 0.661 ± 0.002 | 0.655 ± 0.009 |
| CONCAT | 0.693 ± 0.019 | 0.681 ± 0.023 | 0.752 ± 0.030 |
| MK-SVM | 0.788 ± 0.018 | 0.759 ± 0.019 | 0.827 ± 0.025 |
| Semi-supervised | |||
| MRI | – | 0.659 ± 0.025 | 0.721 ± 0.039 |
| PET | – | 0.640 ± 0.021 | 0.715 ± 0.024 |
| CSF | – | 0.659 ± 0.002 | 0.659 ± 0.005 |
| CONCAT | – | 0.682 ± 0.022 | 0.781 ± 0.028 |
| MK-SVM | – | 0.757 ± 0.017 | 0.837 ± 0.015 |
Bold best performance across both the feature types and the learning schemes, italics best performance across the feature types in the same learning scheme