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. 2006 Jan 28;12(4):630–635. doi: 10.3748/wjg.v12.i4.630

Table 2.

Relation between frequencies of genotypes of CTLA-4 +49, -318, -1172 CTLA-4 polymorphisms and mean AST and ALT levels in subjects with chronic hepatitis, chronic hepatitis on first course of treatment, inactive carrier, non-responders to first course of treatment

TC 1172 genotype Mean SE
AST 1172 T+C– 35.1944 3.7008
1172 T+C+ 25.3077 2.3325
1172 T–C+ 35.0000 14.0000
TC 318 genotype Mean SE
AST 318 T+C+ 29.1000 5.8299
318 T–C+ 33.5366 3.1455
There are no valid cases for AST. Statistics cannot be computed.
AG 49 genotype Mean SE
AST 49 G+A– 32.6667 6.5362
49 G+A+ 32.3750 3.9811
49 G–A+ 32.8462 4.3960
TC 1172 genotype Mean SE
ALT 1172 T+C– 40.9167 5.0528
1172 T+C+ 28.9231 4.3742
1172 T–C+ 50.0000 20.0000
TC 318 genotype Mean SE
ALT 318 T+C+ 33.5000 7.0683
318 T–C+ 39.3659 4.4751
There are no valid cases for ALT. Statistics cannot be computed.
AG 49 genotype Mean SE
ALT 49 G+A– 43.1111 9.3592
49 G+A+ 40.1875 5.7018
49 G–A+ 35.3077 5.9497