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. 2014 Mar 24;4(1):202–219. doi: 10.3390/brainsci4010202

Figure 1.

Figure 1

Trophic support from MSCs. (A) RT-PCR analysis of rat MSCs at passage 4 showing that, in vitro, MSCs express mRNA for BDNF (brain derived neurotrophic factor), CNTF (ciliary neurotrophic factor), GDNF (glial cell-line derived neurotrophic factor), NGF (nerve growth factor) and NT3 (neurotrophin 3). Control: HPRT; (B) Labeling of brain sections for BDNF (a, some MSCs pointed by the arrows) but not GDNF (b) or CNTF (c) show trophic factors synthesized by MSCs 72 days post-transplantation [28].