Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jun 23;4:5390. doi: 10.1038/srep05390

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014, Macmillan Publishers Limited. All rights reserved

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

PMC Copyright notice

(a) Schematic of adenovirus-Cre mediated recombination of Grp78 floxed alleles and mammary transplantation. (b) Sorted adult mammary epithelial stem and progenitor cells population (red) isolated by FACS from 78^f/f adult glands were transduced ex vivo with adenoviral vectors carrying GFP (Ad-GFP-Con) or GFP and Cre recombinase (Ad-GFP-Cre). GFP positive cells were sorted 16 hours later and used to inoculate de-epithelialized recipient glands. (c) Quantitation of flow cytometric analysis of surface GRP78 positive cells from transplanted Ad-GFP-Con and Ad-GFP-Cre mammary epithelial cells following 12 weeks outgrowth. (d) Representative whole mount mammary glands 6 weeks after transplantation of 78^f/f mammary epithelial cells transduced with Ad-GFP-Con or Ad-GFP-Cre. Ad-GFP-Con: n = 3; Ad-GFP-Cre: n = 9. Scale bar shows 1 cm and is applicable to all sections.