Table 1. Topological parameters of three DEG PPI sub-networks.
PPI sub-network | y = βxa | Number of nodes | Number of edges | R2 | Correlation | Clustering coefficienta | Network centralizationb | Network densityc | Network diameterd |
---|---|---|---|---|---|---|---|---|---|
Downregulated DEGs | y = 226.33x−1.132 | 834 | 7005 | 0.844 | 0.782 | 0.365 | 0.621 | 0.020 | 6 |
Upregulated DEGs | y = 515.01x−1.172 | 1813 | 23380 | 0.814 | 0.662 | 0.331 | 0.803 | 0.014 | 6 |
Total DEGs | y = 849.12x−1.218 | 2458 | 33671 | 0.866 | 0.696 | 0.306 | 0.739 | 0.011 | 6 |
aClustering coefficient is a measure of the degree to which nodes in a graph tend to cluster together.
bNetwork centralization measures the degree of the effect when removing some central nodes in the whole network.
cNetwork density describes the portion of the potential connections in a network that are actual connections.
dNetwork diameter representative of the linear size of a network.