Table 1.

Plasma parameters

	Lean	DIO control ASO	DIO Mogat1 ASO
TAG (mg/dL)	60.4 ± 4.0	53.8 ± 2.5	57.1 ± 4.1
NEFA (mmol/L)	0.57 ± 0.07	0.51 ± 0.04	0.51 ± 0.03
Cholesterol (mg/dL)	48.8 ± 2.5	101.1 ± 13.5*	107.2 ± 12.4*
Insulin (ng/mL)	1.6 ± 0.2	4.5 ± 1.1*	1.9 ± 0.4**
	ob/+	ob/ob control ASO	ob/ob Mogat1 ASO
TAG (mg/dL)	55.5 ± 17.6	130.1 ± 19.2*	71.9 ± 7.3**
NEFA (mmol/L)	0.9 ± 0.1	1.8 ± 0.2*	1.6 ± 0.1*
Cholesterol (mg/dL)	99.5 ± 12.8	168.9 ± 18.0*	190.2 ± 24.4*
Insulin (ng/mL)	0.9 ± 0.1	9.9 ± 0.8*	7.6 ± 1.0**

Data are mean ± SE. Plasma was collected at sacrifice after a 4-h fast. NEFA, nonesterified fatty acid.

*P < 0.05 vs. lean controls.

**P < 0.05 vs. ASO control and lean controls.