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. 2014 Jun 14;63(7):2464–2473. doi: 10.2337/db13-0835

Figure 6.

Figure 6

C57BL/6J mice were first fed with HFD for 4 weeks and then continuously treated with HFD in the absence (control) or presence of BF175 (0.2% in HFD) for an additional 8 weeks. A: Body weight gains during the treatment period of 8 weeks. B: Food intake in the last week of treatment. Effects of BF175 by subcutaneous administration for a week under HFD on energy expenditure (C) and physical activity (D) in mice as analyzed by calorimetry. Data represent the mean ± SD (n = 6, or n = 4 for calorimetry experiments). *P < 0.05; #P < 0.01 vs. control (HFD only).