Table 2.
Increase in area of confluent lens epithelial cells in relation to clinical parameters.
| Parameter | Cell Growth (% Increased Area of Confluent HLEC)† | ||
|---|---|---|---|
| 1st week | 2nd Week | Total Period | |
| Age | R=0.019 | R=-0.137† | R=-0.073 |
| Sex | |||
| Female | 69 (11-141) | 80 (46-114) | 231 (159-327) |
| Male | 55 (20-110) | 76 (52-113) | 201 (140-276)§ |
| Pseudoexfoliation present | |||
| Yes | 56 (11-149) | 69 (45-110) | 203 (117-324) |
| No | 64 (19-128) | 80 (50-114) | 218 (154-320) |
| History of uveitis | |||
| Yes | 89 (24-159) | 126 (70-134) | 238 (174-328) |
| No | 64 (14-133) | 79 (49-113) | 215 (142-321) |
| Diabetes | |||
| Yes | 29 (3-82)¶ | 90 (60-127) | 180 (109-264) |
| No | 69 (19-139) | 78 (49-114) | 219 (154-322) |
| Xylocain in AC | |||
| Yes | 62 (14-131) | 86 (50-118) | 217 (157-332) |
| No | 64 (15-134) | 75 (46-110) | 211 (139-313) |
| Trypan blue in AC | |||
| Yes | 60 (1-69) | 72 (25-97) | 158 (27-232) |
| No | 64 (17-134) | 80 (50-116) | 217 (151-322) |
†Cell growth was calculated as the increase in area of confluent HLEC the 1st week (day 1-7) and the 2nd week (day 8-14) respectively, as related to the area of the lens capsule. In addition, the increase in area of confluent HLEC after two weeks of cell culture was determined in relation to the lens capsule (total period, day 1-14). Data are presented as median with 25th and 75th percentiles, unless otherwise stated. HLEC=human lens epithelial cells. R=correlation coefficient. After Bonferroni correction for multiple comparisons (three different time points), significance was set at P<0.017. ‡p=0.035, Spearman's rho correlation test. §p=0.037, Mann-Whitney U-test. ¶p=0.005, Mann-Whitney U-test. AC=anterior chamber.