. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: J Endocrinol. 2014 Jul;222(1):27–41. doi: 10.1530/JOE-13-0455

Table 3.

Adiposity, serum leptin and BAT UPC1 levels following leptin or leptin antagonist overexpression in NTS from Exp. 4.

	rAAV-Control	rAAV-Leptin into NTS	rAAV-Antagonist into NTS
Adiposity, g	5.43± 0.34	4.45± 0.67	6.07± 0.31
Serum Leptin (ng/ml)	2.80 ± 0.23^a	1.72 ± 0.41^b	3.46 ± .32^c
UCP1/ μg Arbitrary units	100 ± 8.2^a	134.2± 7.3^b	113.9± 7.5

Data represent the mean ± SE of 7 rats/group.

Adiposity represents the sum of perirenal, retroperitoneal and epididymal white adipose tissues at death.

The value of UCP1, expressed as UCP1/ μg BAT protein, in rAAV-Control for is arbitrarily set to 100 with SE adjusted proportionally with remaining groups normalized to the level in rAAV-Control.

P<0.005 (Serum leptin) or P<0.05 (UCP1) for difference among groups at day 20 by one-way ANOVA.

P<0.05 for difference from control group by Newman-Keuls post-hoc analysis.

P<0.01 for difference from rAAV-Leptin into NTS by Newman-Keuls post-hoc analysis.