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Comparison of the molecular beacon (MB) probe and differential fluorescent receptor (DFR) approaches for the analysis of SNP containing nucleic acids. A) MB probe does not hybridize to mismatched DNA sequence (the analytes are shown as dashed lines). B) MB probe hybridizes to matched DNA analyte. C) DFR consists of a dumbbell molecular beacon (DMB) probe and four adaptor strands. DFR forms a highly fluorescent complex with a fully matched analyte.
