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. Author manuscript; available in PMC: 2014 Jun 23.
Published in final edited form as: Exp Lung Res. 2012 Aug 16;38(8):383–395. doi: 10.3109/01902148.2012.714841

Figure 1. Absence of PKCε activity confirmed in lung slices from PKCε deficient mice.

Figure 1

Precision-cut lung slices from wild-type (WT, Prkce+/+) and knock-out (KO, Prkce−/−) mice were ex vivo treated with phorbol 12-myristate 13-acetate (PMA, 200 ng/ml, positive control), organic dust extract (5% ODE), or media alone in submerged in vitro culture. PKCε activity was assayed from 1-24 hr. Results represent mean ± SEM (N=5-6 per condition) with statistical significance denoted by asterisks (**p<0.01, ***p<0.001) versus media alone, and hatch marks (###p<0.001) denotes difference between matched WT and KO conditions.