Table 3.
Independent relationships of total adiponectin concentrations (1 SD increment) with carotid atherosclerosis in all RA patients and subgroups.
| Groups | cIMT | Plaque | ||
|---|---|---|---|---|
| Partial R | P | OR (95% CI) | P | |
| All | 0.042 | 0.6 | 0.98 (0.91–1.05) | 0.6 |
| Population | ||||
| Black | −0.153 | 0.1 | 1.08 (0.94–1.30) | 0.9 |
| White | 0.131 | 0.2 | 0.89 (0.77–1.01) | 0.07 |
| Age >55 years | ||||
| Yes | 0.031 | 0.8 | 0.98 (0.89–1.07) | 0.07 |
| No | 0.023 | 0.8 | 0.92 (0.75–1.02) | 0.08 |
| ≥1 major risk factors | ||||
| Yes | −0.023 | 0.9 | 0.95 (0.89–1.01) | 0.09 |
| No | 0.041 | 0.6 | 1.05 (0.90–1.02) | 0.5 |
| Obesity | ||||
| Yes | 0.068 | 0.6 | 0.93 (0.84–1.02) | 0.1 |
| No | 0.040 | 0.7 | 0.99 (0.90–1.09) | 0.9 |
| MetS waist | ||||
| Yes | 0.112 | 0.3 | 0.87 (0.76–0.99) | 0.02 |
| No | 0.003 | 1.0 | 1.08 (0.92–1.13) | 0.7 |
| RA duration >10 years | ||||
| Yes | 0.129 | 0.2 | 0.94 (0.83–1.03) | 0.2 |
| No | −0.078 | 0.5 | 1.05 (0.94–1.15) | 0.4 |
| CDAI >10 | ||||
| Yes | −0.017 | 0.9 | 0.92 (0.78–1.06) | 0.2 |
| No | 0.090 | 0.4 | 0.99 (0.90–1.08) | 0.7 |
| ESR >12 | ||||
| Yes | −0.072 | 0.5 | 0.96 (0.84–1.08) | 0.4 |
| No | 0.129 | 0.2 | 0.97 (0.87–1.08) | 0.6 |
| Deformed joints | ||||
| Yes | 0.068 | 0.4 | 1.00 (0.90–1.10) | 0.9 |
| No | −0.193 | 0.2 | 0.94 (0.88–0.99) | 0.03 |
| Rheumatoid factor positive | ||||
| Yes | 0.023 | 0.8 | 0.99 (0.94–1.04) | 0.9 |
| No | 0.091 | 0.6 | 0.91 (0.72–1.10) | 0.3 |
Relationships were determined in Framingham score, race, glomerular filtration rate, waist circumference, and C-reactive protein concentrations adjusted models. Significant associations are shown in bold. SD: standard deviation; cIMT: carotid intima-media thickness; OR: odds ratio; CI: confidence interval; RA: rheumatoid arthritis; MetS: metabolic syndrome; CDAI: Clinical Disease Activity Index; ESR: erythrocyte sedimentation rate.