Table 4.
Independent relationships of high molecular weight adiponectin concentrations (1 SD increment) with carotid atherosclerosis in all RA patients and subgroups.
| Groups | cIMT | Plaque | ||
|---|---|---|---|---|
| Partial R | P | OR (95% CI) | P | |
| All | −0.008 | 0.9 | 0.99 (0.96–1.02) | 0.6 |
| Population | ||||
| Black | −0.173 | 0.08 | 1.04 (0.94–1.33) | 0.9 |
| White | 0.071 | 0.5 | 0.96 (0.95–1.01) | 0.1 |
| Age >55 years | ||||
| Yes | −0.057 | 0.6 | 0.99 (0.94–1.04) | 0.07 |
| No | 0.008 | 0.9 | 0.95 (0.91–1.01) | 0.1 |
| ≥1 major risk factors | ||||
| Yes | −0.042 | 0.8 | 0.96 (0.92–1.01) | 0.07 |
| No | −0.035 | 0.7 | 1.01 (0.95–1.12) | 0.4 |
| Obesity | ||||
| Yes | −0.008 | 1.0 | 0.96 (0.90–1.01) | 0.1 |
| No | −0.011 | 0.9 | 1.00 (0.96–1.05) | 1.0 |
| MetS waist | ||||
| Yes | −0.035 | 0.7 | 0.92 (0.85–0.99) | 0.02 |
| No | −0.006 | 1.0 | 1.02 (0.94–1.06) | 0.6 |
| RA duration >10 years | ||||
| Yes | 0.059 | 0.6 | 0.97 (0.92–1.02) | 0.2 |
| No | −0.091 | 0.4 | 1.02 (0.97–1.07) | 0.5 |
| CDAI >10 | ||||
| Yes | 0.005 | 1.0 | 0.94 (0.86–1.02) | 0.2 |
| No | −0.002 | 1.0 | 1.00 (0.96–1.04) | 0.9 |
| ESR >12 | ||||
| Yes | −0.013 | 0.9 | 0.96 (0.84–1.08) | 0.3 |
| No | 0.038 | 0.7 | 0.99 (0.96–1.04) | 0.7 |
| Deformed joints | ||||
| Yes | 0.018 | 0.8 | 1.00 (0.96–1.05) | 0.8 |
| No | −0.140 | 0.4 | 0.94 (0.89–0.99) | 0.03 |
| Rheumatoid factor positive | ||||
| Yes | 0.008 | 0.9 | 1.00 (0.96–1.03) | 0.8 |
| No | −0.024 | 0.9 | 0.96 (0.86–1.05) | 0.3 |
Relationships were determined in Framingham score, race, glomerular filtration rate, waist circumference, and C-reactive protein concentrations adjusted models. Significant associations are shown in bold. SD: standard deviation; cIMT: carotid intima-media thickness; OR: odds ratio; CI: confidence interval; RA: rheumatoid arthritis; MetS: metabolic syndrome; CDAI: Clinical Disease Activity Index; ESR: erythrocyte sedimentation rate.