Skip to main content
. 2014 Apr 29;42(11):e92. doi: 10.1093/nar/gku324

Figure 3.

Figure 3.

Identification of LMNA occupancy sites by ChIP-seq. (a) IGV browser views of LMNA occupancy throughout chromosome 7 in AD04DF (both ChIP-seq replicates) and LDF. Tracks show genes, FPKM values from RNA-seq data (AD04DFs) and LMNA log ChIP/Input ratios. (b) ChIP-qPCR analysis of LMNA enrichment on indicated promoter and intergenic sites (mean ± SD from three experiments) in AD04DF. LAD information (+, within LAD; -, outside LAD) is from our subsequent LAD discovery using EDD. ChIP-qPCR data are consistent with LAD identification by ChIP-seq.