Table 2. Genomic distribution of inferred loci with nucleosomal depletion in TGFβ stimulated cells with associated over-represented TF binding motifs in defined categories according to distance from exons and genes and their association with genes and expression changes.

	Exonic	Intronic proximal	Intronic distal	Intergenic proximal	Intergenic distal
Number of loci	199	2802	2469	245	9859
Percentage of total loci	43.8	54.3	57.6	14.2	77.7
TFs	SPI1, ELF5, FEV, CTCF, ETS1, Hltf	Hand1::Tcfe2a, SPI1, NFE2L2, SOX10, NFATC2, FEV, Mafb, EBF1, CTCF	MZF1_1–4, PLAG1, MZF1_5–13, SPI1, RUNX1, NFATC2, EBF1, SOX10, FEV, BRCA1	SPI1, FEV	NFATC2, EBF1, Myf, SPIB, SOX10, PPARG::RXRA, Hand1::Tcfe2a, NR2F1, Gfi, INSM1, SPI1, FEV, MZF1_1–4, Mafb, HNF4A, RREB1, En1, BRCA1
Number of associated genes	182	2503	1539	279
Number of loci associated with gene expression change	45	607	1173	56
TFs associated with gene expression change	SPI1, Hltf, ELF5, FEV, CTCF, ETS1	FEV, SPI1, Hand1::Tcfe2a, Mafb, EBF1, NFE2L2, SOX10, NFATC2, CTCF	MZF1_5–13, MZF1_1–4, PLAG1, EBF1, SPI1, FEV, NFATC2, RUNX1, SOX10, BRCA1	SPI1, FEV
Number of associated genes with expression change	21	290	306	38
Number of associated exons	225	9229
Number of loci associated with exon expression change	64	1711
TFs associated with exon expression change	SPI1, ELF5, ETS1, CTCF, FEV, Hltf	NFE2L2, FEV, SOX10, Hand1::Tcfe2a, SPI1, Mafb, EBF1, CTCF, NFATC2
Number of associated exons with expression change	30	1498