Table 1. (A) Numbers of introns and isoforms in monomorphic (mono) and polymorphic (poly) genes in the human genome (hg18 and hg19). (B) Distributions of constitutive and alternative nucleotides located in the core (cCDS alt) or terminal (5grey alt, 5grey dual, 3grey alt, 3grey dual) coding regions of polymorphic gene loci (Ensembl, hg19).
| A. | ||||||
|---|---|---|---|---|---|---|
| Gene group | Intron # max | Intron # mean | # of isoforms | |||
| B. | ||||||
| CDS con | cCDS alt | 5grey alt | 5grey dual | 3grey alt | 3grey dual | |
| hg18 | ||||||
| Mono+Poly | 10.14 ± 0.63 | 8.9 ± 0.40 | ||||
| Mono | 7.98 ± 0.61 | 7.98 ± 0.61 | 1 | |||
| Poly | 13.02 ± 0.13 | 10.65 ± 0.53 | 3.56 ± 0.13 | |||
| hg19 | ||||||
| Mono+Poly | 10.35 ± 0.11 | 8.9 ± 0.12 | ||||
| Mono | 7.8 ± 0.11 | 7.8 ± 0.11 | 1 | |||
| Poly | 12.99 ± 0.1 | 9.8 ± 0.08 | 4.07 ± 0.02 | |||
| # seq | 17 718 | 11 811 | 7 524 | 5 011 | 10 397 | 6 145 |
| average nt | 866.6 | 200.2 | 283.0 | 133.0 | 496.2 | 378.3 |
| # nt | 14 674 986 | 2 364 981 | 2 129 403 | 666 591 | 5 159 400 | 2 324 934 |
| Sum terminal alternative (with dual) | ||||||
| # nt | 10 280 328 | |||||
| Sum total alternative (with dual) | ||||||
| # nt | 12 645 309 | |||||
Abbreviations: con,constitutive; alt, alternative, dual, dual function; nt, nucleotides; seq, sequences.