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. 2014 Apr 29;42(11):7395–7408. doi: 10.1093/nar/gku349

Figure 6.

Figure 6.

(A) Mechanistic model proposition. Schematic representation of the favored HADDOCK-best InterEvScore model, summarizing the functional residues and zones studied. (B) Global structural model for the assembly between DprA, RecA and ssDNA integrating the structural information provided by two other studies: (a) the first monomer in the structure of the EcRecA filament bound to ssDNA (PDB: 3CMW (2)) was superimposed with the structure of the SpRecA model assembled with the SpDprA dimer as in the best HADDOCK/InterEvScore model. (b) The location of the ssDNA complexed to SpDprA was approximately modeled by superimposing the structure of HpDprA (PDB: 4LJR) on the first monomer of SpDprA (PDB: 3UQZ).