Table 2. The observed type I error rate when testing for differential enrichment using counts from each peak calling strategy. Error rates for a range of specified error thresholds are shown. All values represent the mean of 10 simulation iterations with the standard error shown in brackets. RA: reference analysis using 10 000 randomly chosen true peaks.
ID | Error rate | ||
---|---|---|---|
0.01 | 0.05 | 0.1 | |
RA | 0.010 (0.000) | 0.051 (0.001) | 0.100 (0.002) |
1 | 0.002 (0.000) | 0.019 (0.001) | 0.053 (0.001) |
2 | 0.003 (0.000) | 0.030 (0.000) | 0.073 (0.001) |
3 | 0.006 (0.000) | 0.042 (0.001) | 0.092 (0.001) |
4 | 0.033 (0.001) | 0.145 (0.001) | 0.261 (0.002) |
5 | 0.000 (0.000) | 0.001 (0.000) | 0.005 (0.000) |
6 | 0.088 (0.006) | 0.528 (0.013) | 0.893 (0.006) |
7 | 0.010 (0.000) | 0.049 (0.001) | 0.098 (0.001) |