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Cytokine expression in lungs of OVA-treated wild-type and IL-4R KO mice. Wild-type or IL-4R KO mice were sensitized and challenged with OVA and inoculated with sham or RV. (A) After 24 h, lungs were collected and gene expression measured by qPCR. (B) TNF-α, IL-12p40 and IL-17A protein in the BAL fluid was assessed with multiplex immune assay. (Mean ± SEM, n = 3-6 each group, *different from sham, P < 0.05, one-way ANOVA; †different from wild-type, P < 0.05, one-way ANOVA).
