Effects of combined exposure of SeMet (50 μM) and hypersaline
conditions on the development and hatchability of Japanese medaka
embryos after exposure at 12 hpf. White bars represent freshwater
and black bars represent saltwater. (A) Percent hatch, (B) median
day to hatch, (C) percent deformities in hatched embryos, (D) examples
of deformities; control is top image, bottom two images demonstrate
lordosis, kyphosis, cranio-facial abnormalities, and yolk-sac edema.
Each value represents the mean ± standard error (SE) of 5–10
replicates. Statistical significance is indicated by differing letters
(Two-way ANOVA, Tukey HSD test, or Kruskal–Wallis, Dunn’s
test p ≤ 0.05).