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. 2014 May 20;48(12):7018–7025. doi: 10.1021/es502076j

Table 3. Percent Change (95% Confidence Interval)a in Plasma Inflammation Biomarker in Association with Interquartile Range Increase in Urinary Phthalate Metabolite Concentration.

  CRP
IL-1β
IL-6
  %Δ (95% CI) p %Δ (95% CI) p %Δ (95% CI) p
MEHP 8.55 (−7.27, 27.1) 0.31 5.41 (−12.0, 26.3) 0.57 15.9 (−4.58, 40.8) 0.14
MEHHP 4.13 (−9.33, 19.6) 0.57 5.31 (−9.93, 23.1) 0.52 15.8 (−2.23, 37.2) 0.09
MEOHP 4.14 (−9.55, 19.9) 0.57 5.91 (−9.68, 24.2) 0.48 16.9 (−1.57, 38.9) 0.08
MECPP 4.25 (−9.95, 20.7) 0.58 8.06 (−8.37, 27.4) 0.36 18.8 (−0.59, 42.1) 0.06
MCPP 13.0 (−1.23, 29.4) 0.08 –4.50 (−18.1, 11.3) 0.56 2.87 (−13.0, 21.7) 0.74
MCOP 4.21 (−9.48, 20.0) 0.57 6.12 (−9.78, 24.8) 0.48 2.61 (−13.9, 22.3) 0.77
MCNP 10.1 (−0.86, 22.2) 0.08 10.4 (−1.93, 24.3) 0.11 16.8 (2.69, 32.9) 0.02
MBzP –1.67 (−16.7, 16.1) 0.84 –11.6 (−26.7, 6.55) 0.20 –1.50 (−19.8, 21.0) 0.89
MBP 9.68 (−5.18, 26.9) 0.22 0.97 (−14.4, 19.1) 0.91 –0.73 (−17.1, 18.8) 0.94
MiBP 1.79 (−11.6, 17.3) 0.81 –0.04 (−14.9, 17.3) 1.00 –1.15 (−17.0, 17.7) 0.90
MEP –2.22 (−18.4, 17.1) 0.81 –3.69 (−21.9, 18.7) 0.73 7.70 (−14.0, 34.9) 0.52
  IL-10
TNF-α
  %Δ (95%CI) p %Δ (95%CI) p
MEHP 17.2 (−2.36, 40.7) 0.09 4.51 (−4.34, 14.2) 0.33
MEHHP 15.8 (−1.10, 35.7) 0.07 4.13 (−3.38, 12.2) 0.29
MEOHP 17.6 (0.18, 38.1) 0.05 4.48 (−3.16, 12.7) 0.26
MECPP 24.5 (5.53, 46.9) 0.01 4.90 (−3.00, 13.5) 0.24
MCPP 2.63 (−12.3, 20.1) 0.75 –0.13 (−7.32, 7.62) 0.97
MCOP 18.0 (0.02, 39.2) 0.05 1.42 (−6.53, 10.0) 0.74
MCNP 7.73 (−4.54, 21.6) 0.23 0.26 (−5.21, 6.03) 0.93
MBzP –17.8 (−31.9, −0.75) 0.05 1.31 (−7.70, 11.2) 0.78
MBP –8.28 (−22.4, 8.33) 0.31 3.54 (−4.35, 12.1) 0.39
MiBP –5.02 (−19.3, 11.8) 0.54 2.54 (−5.10, 10.8) 0.53
MEP –7.50 (−25.3, 14.5) 0.48 1.91 (−8.35, 13.3) 0.73
a

Estimates created from linear mixed models with random slopes for subject ID and adjustment for urinary specific gravity, visit of sample collection, and maternal prepregnancy BMI, education, and income level. N = 87 subjects; N = 157 observations.