Table 3. Percent Change (95% Confidence Interval)a in Plasma Inflammation Biomarker in Association with Interquartile Range Increase in Urinary Phthalate Metabolite Concentration.
CRP |
IL-1β |
IL-6 |
||||
---|---|---|---|---|---|---|
%Δ (95% CI) | p | %Δ (95% CI) | p | %Δ (95% CI) | p | |
MEHP | 8.55 (−7.27, 27.1) | 0.31 | 5.41 (−12.0, 26.3) | 0.57 | 15.9 (−4.58, 40.8) | 0.14 |
MEHHP | 4.13 (−9.33, 19.6) | 0.57 | 5.31 (−9.93, 23.1) | 0.52 | 15.8 (−2.23, 37.2) | 0.09 |
MEOHP | 4.14 (−9.55, 19.9) | 0.57 | 5.91 (−9.68, 24.2) | 0.48 | 16.9 (−1.57, 38.9) | 0.08 |
MECPP | 4.25 (−9.95, 20.7) | 0.58 | 8.06 (−8.37, 27.4) | 0.36 | 18.8 (−0.59, 42.1) | 0.06 |
MCPP | 13.0 (−1.23, 29.4) | 0.08 | –4.50 (−18.1, 11.3) | 0.56 | 2.87 (−13.0, 21.7) | 0.74 |
MCOP | 4.21 (−9.48, 20.0) | 0.57 | 6.12 (−9.78, 24.8) | 0.48 | 2.61 (−13.9, 22.3) | 0.77 |
MCNP | 10.1 (−0.86, 22.2) | 0.08 | 10.4 (−1.93, 24.3) | 0.11 | 16.8 (2.69, 32.9) | 0.02 |
MBzP | –1.67 (−16.7, 16.1) | 0.84 | –11.6 (−26.7, 6.55) | 0.20 | –1.50 (−19.8, 21.0) | 0.89 |
MBP | 9.68 (−5.18, 26.9) | 0.22 | 0.97 (−14.4, 19.1) | 0.91 | –0.73 (−17.1, 18.8) | 0.94 |
MiBP | 1.79 (−11.6, 17.3) | 0.81 | –0.04 (−14.9, 17.3) | 1.00 | –1.15 (−17.0, 17.7) | 0.90 |
MEP | –2.22 (−18.4, 17.1) | 0.81 | –3.69 (−21.9, 18.7) | 0.73 | 7.70 (−14.0, 34.9) | 0.52 |
IL-10 |
TNF-α |
|||
---|---|---|---|---|
%Δ (95%CI) | p | %Δ (95%CI) | p | |
MEHP | 17.2 (−2.36, 40.7) | 0.09 | 4.51 (−4.34, 14.2) | 0.33 |
MEHHP | 15.8 (−1.10, 35.7) | 0.07 | 4.13 (−3.38, 12.2) | 0.29 |
MEOHP | 17.6 (0.18, 38.1) | 0.05 | 4.48 (−3.16, 12.7) | 0.26 |
MECPP | 24.5 (5.53, 46.9) | 0.01 | 4.90 (−3.00, 13.5) | 0.24 |
MCPP | 2.63 (−12.3, 20.1) | 0.75 | –0.13 (−7.32, 7.62) | 0.97 |
MCOP | 18.0 (0.02, 39.2) | 0.05 | 1.42 (−6.53, 10.0) | 0.74 |
MCNP | 7.73 (−4.54, 21.6) | 0.23 | 0.26 (−5.21, 6.03) | 0.93 |
MBzP | –17.8 (−31.9, −0.75) | 0.05 | 1.31 (−7.70, 11.2) | 0.78 |
MBP | –8.28 (−22.4, 8.33) | 0.31 | 3.54 (−4.35, 12.1) | 0.39 |
MiBP | –5.02 (−19.3, 11.8) | 0.54 | 2.54 (−5.10, 10.8) | 0.53 |
MEP | –7.50 (−25.3, 14.5) | 0.48 | 1.91 (−8.35, 13.3) | 0.73 |
Estimates created from linear mixed models with random slopes for subject ID and adjustment for urinary specific gravity, visit of sample collection, and maternal prepregnancy BMI, education, and income level. N = 87 subjects; N = 157 observations.