Table 4. Percent Change (95% Confidence Interval)a in Urinary Oxidative Stress Biomarker in Association with Interquartile Range Increase in Urinary Phthalate Metabolite Concentration.
OHdG |
Isoprostane |
|||
---|---|---|---|---|
%Δ (95% CI) | p | %Δ (95% CI) | p | |
MEHP | 17.7 (2.35, 35.3) | 0.03 | 34.9 (15.9, 57.1) | <0.01 |
MEHHP | 14.5 (0.73, 30.2) | 0.04 | 30.2 (13.5, 49.3) | <0.01 |
MEOHP | 17.9 (3.00, 34.9) | 0.02 | 34.3 (16.4, 55.0) | <0.01 |
MECPP | 15.1 (0.34, 32.1) | 0.05 | 28.4 (10.9, 48.7) | <0.01 |
MCPP | 2.31 (−9.31, 15.4) | 0.71 | 23.7 (9.04, 40.4) | <0.01 |
MCOP | 3.18 (−8.22, 16.0) | 0.60 | 24.2 (8.94, 41.6) | <0.01 |
MCNP | 7.72 (−2.62, 19.2) | 0.15 | 18.9 (6.94, 32.2) | <0.01 |
MBzP | 13.3 (−3.35, 32.8) | 0.13 | 35.3 (14.5, 59.9) | <0.01 |
MBP | 23.9 (9.37, 40.4) | <0.01 | 49.7 (32.0, 69.8) | <0.01 |
MiBP | 19.9 (5.52, 36.2) | 0.01 | 48.8 (30.4, 69.8) | <0.01 |
MEP | 11.4 (−5.50, 31.3) | 0.20 | 19.4 (−1.56, 44.8) | 0.08 |
Estimates created from linear mixed models with random slopes for subject ID and adjustment for urinary specific gravity, visit of sample collection, and maternal prepregnancy BMI, education, and income level. N = 46 subjects; N = 125 observations.