Table 1.
Correlation between Wnt5a and clinicopathological features in NSCLC.
| Variant | Total | Wnt5a | x 2 | P value | |
|---|---|---|---|---|---|
| n | Negative (%) | Positive (%) | |||
| Gender | |||||
| Male | 145 | 47 (32.41) | 98 (67.59) | 6.674 | 0.012 |
| Female | 60 | 31 (51.67) | 29 (48.33) | ||
| Age (yr) | |||||
| <60 | 101 | 37 (36.63) | 64 (63.37) | 0.169 | 0.774 |
| ≥60 | 104 | 41 (39.42) | 63 (60.58) | ||
| Size (cm) | |||||
| <3 | 29 | 11 (37.93) | 18 (62.07) | 0.000 | 1.000 |
| ≥3 | 176 | 67 (38.07) | 109 (61.93) | ||
| Location | |||||
| Center | 106 | 38 (35.85) | 68 (64.15) | 0.451 | 0.565 |
| Peripheral | 99 | 40 (40.40) | 59 (59.60) | ||
| Histological classification | |||||
| SCC | 79 | 23 (29.11) | 56 (70.89) | 8.222 | 0.016 |
| AC | 75 | 38 (50.67) | 37 (49.33) | ||
| LCC | 51 | 17 (33.33) | 34 (66.67) | ||
| Differentiation | |||||
| Well | 35 | 17 (48.57) | 18 (51.43) | 2.044 | 0.360 |
| Moderate | 87 | 32 (36.78) | 55 (63.22) | ||
| Poor | 83 | 29 (34.94) | 54 (65.06) | ||
| Pleura invasion | |||||
| No | 113 | 39 (34.51) | 74 (65.49) | 1.335 | 0.252 |
| Yes | 92 | 39 (42.39) | 53 (57.61) | ||
| Lymph node metastasis | |||||
| No | 117 | 45 (38.46) | 72 (61.54) | 0.020 | 1.000 |
| Yes | 88 | 33 (37.50) | 55 (62.50) | ||
| T stage | |||||
| T1 + T2 | 149 | 56 (37.58) | 93 (62.42) | 0.050 | 0.872 |
| T3 + T4 | 56 | 22 (39.29) | 34 (60.71) | ||
| Clinical stage | |||||
| I + II | 158 | 62 (39.24) | 96 (60.76) | 0.415 | 0.609 |
| III + IV | 47 | 16 (34.04) | 31 (65.96) | ||
| Distant metastasis | |||||
| No | 147 | 57 (38.78) | 90 (61.22) | 0.116 | 0.752 |
| Yes | 58 | 21 (36.21) | 37 (63.79) | ||
| Therapy before surgery | |||||
| No | 186 | 69 (37.10) | 117 (62.90) | 0.772 | 0.458 |
| Yes | 19 | 9 (47.37) | 10 (52.63) | ||
P < 0.05 means statistical significance.