Table 2.
Relationship between Wnt5a and angiogenesis, expression of related proteins, and β-catenin nuclear expression in NSCLC.
| Variant | Total | Wnt5a | P value | r | |
|---|---|---|---|---|---|
| n | Negative (%) | Positive (%) | |||
| CD34-MVD | |||||
| <28 | 92 | 52 (56.52) | 40 (43.48) | 0.026 | 0.157 |
| ≥28 | 113 | 46 (40.71) | 67 (59.29) | ||
| VM | |||||
| Negative | 177 | 73 (41.24) | 104 (58.76) | 0.021 | 0.165 |
| Positive | 28 | 5 (17.86) | 23 (82.14) | ||
| VE-cadherin | |||||
| Negative | 104 | 50 (48.08) | 54 (51.92) | 0.004 | 0.210 |
| Positive | 101 | 28 (27.72) | 73 (72.28) | ||
| MMP2 | |||||
| Negative | 138 | 65 (47.10) | 73 (52.90) | <0.001 | 0.268 |
| Positive | 67 | 13 (19.40) | 54 (80.60) | ||
| MMP9 | |||||
| Negative | 125 | 58 (46.40) | 67 (53.60) | 0.003 | 0.215 |
| Positive | 80 | 20 (25.00) | 60 (75.00) | ||
| β-Catenin nuclear expression | |||||
| Negative | 173 | 72 (41.62) | 101 (58.38) | 0.017 | 0.171 |
| Positive | 32 | 6 (18.75) | 26 (81.25) | ||
P < 0.05 means statistical significance.