. Author manuscript; available in PMC: 2014 Jun 23.

Published in final edited form as: Nat Rev Genet. 2013 Mar 12;14(4):262–274. doi: 10.1038/nrg3425

Table 1.

Summary of organismal examples of selection at linked sites.^*

organism	genome-scale analysis^a	SLS inference^a			neutral polymorphism correlated with^b:			recombination rate correlated with^b:				key references
organism	genome-scale analysis^a	strength	RHH	BGS	rec. rate	repl. site divergence	gene density	codon bias	site freq. spectrum	repl. site divergence	neutral site divergence	key references
Mammals

Homo sapiens	+	moderate	(+)	+	+		−		+	o	+	^{23, 24, 31, 134, 147, 148}

Mus musculus					+						o	^{149, 150}
Birds

Gallus gallus					+				o		o	^{151, 152}

Insects

Anopheles gambiae			+		+				(+)			¹⁵³

Drosophila melanogaster	+	strong	+	+	+	−		+	+	+	o	^{6, 10, 29, 39, 40, 49, 154–156}

Drosophila persimilis					+			+			o	¹³²

Drosophila pseudoobscura	+	moderate	(+)		+	−				o	o(+)	^{106, 135, 157}

Drosophila simulans	+	strong	+		+	−	−				(+)	^{30, 47}

Nematodes

Caenorhabditis briggsae		strong		+	+				(+)	−	(+)	⁵⁹

Caenorhabditis elegans	+	strong	+	+	+		−	o	+	(+)	o(+)	^{62, 63, 158, 159}

Caenorhabditis remanei					o						(o)	¹⁶⁰

Fungi

Saccharomyces cerevisiae	+	weak			+	−	(+)	(+)	o	(−)	(−)	^{56, 137, 161–164}

Plants
Aegilops spp.					+							¹⁶⁵

Arabidopsis thaliana	+	weak		+	o(+)	o	−	o	o	o		^{32, 55, 166–168}

Arabidopsis lyrata		weak	−		o		o	o		o	o	^{54, 167}

Beta vulgaris					+						o	¹⁶⁹

Lycopersicon spp.		weak		+	o(+)						o	^{53, 116, 170, 171}

Medicago truncatula	+			+	+		−					¹⁷²

Oryza sativa		weak	+	+	−		−				+	^{36, 173}

Oryza rufipogon		moderate		+	o/−		−				+	³⁶

Zea mays		weak	−	+	o(+)				o		o	^{57, 174, 175}

studies of non-recombining chromosomes not included;

a ‘+’ indicates affirmative evidence, ‘−’ indicates refuting evidence;

a ‘+’ indicates positive correlation, ‘−’ indicates negative correlation, ‘o’ indicates no correlation; values in parenthesis indicate weak or marginally-significant effect; RHH = recurrent genetic hitchhiking; BGS = background selection