Table 4.
Symptom Outcomes at Most Recent Clinical Follow-Up
| Symptom Outcomes | Total, n (%) | Fundoplication Alone, n (%) | Fundoplication With Collis, n (%) | p Value |
|---|---|---|---|---|
| Time to clinical follow-up, months, median (IQR) | 26 (12,50) | 20 (9, 36) | 33 (16,60) | <0.001 |
| Dysphagiaa | ||||
| Assessed | 614 | 233 | 381 | |
| Resolved | 188 (67) | 76 (72) | 112 (63) | 0.117 |
| Persistent | 94 (33) | 29 (28) | 65 (37) | |
| New postoperatively | 55 (17) | 15 (12) | 40 (20) | 0.06 |
| Heartburna | ||||
| Assessed | 642 | 259 | 383 | |
| Resolved | 315 (71) | 127 (70) | 188 (72) | 0.624 |
| Persistent | 126 (29) | 54 (30) | 72 (28) | |
| New postoperatively | 37 (18) | 14 (18) | 23 (19) | 0.894 |
| Regurgitationa | ||||
| Assessed | 547 | 202 | 345 | |
| Resolved | 296 (89) | 104 (88) | 192 (89) | 0.746 |
| Persistent | 37 (11) | 14 (12) | 23 (11) | |
| New postoperatively | 19 (9) | 8 (10) | 11 (8) | 0.79 |
| Epigastric or chest paina | ||||
| Assessed | 598 | 244 | 354 | |
| Resolved | 291 (80) | 104 (69) | 187 (87) | <0.001 |
| Persistent | 75 (20) | 47 (31) | 28 (13) | |
| New postoperatively | 41 (16) | 15 (16) | 26 (19) | 0.614 |
| Postprandial bloatinga | ||||
| Assessed | 580 | 231 | 349 | |
| Resolved | 128 (61) | 39 (48) | 89 (69) | 0.003 |
| Persistent | 82 (39) | 42 (52) | 40 (31) | |
| New postoperatively | 126 (34) | 63 (42) | 63 (29) | 0.008 |
| Shortness of breatha | ||||
| Assessed | 574 | 230 | 344 | |
| Resolved | 218 (78) | 79 (70) | 139 (83) | 0.011 |
| Persistent | 63 (22) | 34 (30) | 29 (17) | |
| New postoperatively | 38 (13) | 13 (11) | 25 (14) | 0.44 |
| Proton pump inhibitor usea | ||||
| Assessed | 612 | 235 | 377 | |
| Resolved | 257 (55) | 94 (51) | 163 (57) | 0.297 |
| Persistent | 214 (45) | 89 (49) | 125 (43) | |
| New postoperatively | 39 (28) | 14 (27) | 25 (28) | >0.999 |
a
Includes only patients with both preoperative and postoperative symptom assessment. When preoperative symptoms were present, analysis compares proportion of patients in each group with persistent versus resolved symptoms. When symptoms were absent preoperatively, analysis compares proportion of patients in each group with new symptoms. IQR = interquartile range.