Table 3.
S9 Metabolic Stability of Compounds 13 and 14.
| T½ (min)a | |||||
|---|---|---|---|---|---|
| Compound | Rat | Mouse | Dog | Monkey | Human |
| 13 | >200 | >200 | >200 | >200 | 57 |
| 14 | >200 | >200 | >200 | >200 | >200 |
NADPH added
S9 Metabolic Stability of Compounds 13 and 14.
| T½ (min)a | |||||
|---|---|---|---|---|---|
| Compound | Rat | Mouse | Dog | Monkey | Human |
| 13 | >200 | >200 | >200 | >200 | 57 |
| 14 | >200 | >200 | >200 | >200 | >200 |
NADPH added