Table 1.
Differentially transcribed host genes up or down-regulated by >3-fold at 24 h after C. trachomatis infection of CNDT-2 cells compared to non-infected
| Affymetrix ID | Gene name | Gene symbol | Log2 fold change | Absolute fold change |
|---|---|---|---|---|
|
8102800 |
Solute carrier family 7, (cationic amino acid transporter, y + system) member 11 |
SLC7A11 |
3,50 |
11,28 |
|
8154381 |
Chromosome 9 open reading frame 150 |
C9orf150 |
3,25 |
9,51 |
|
7982868 |
ChaC, cation transport regulator homolog 1 (E. coli) |
CHAC1 |
2,63 |
6,18 |
|
7928308 |
DNA-damage-inducible transcript 4 |
DDIT4 |
2,41 |
5,33 |
|
7902290 |
Hystathionase (cystathionine gamma-lyase) |
CTH |
1,89 |
3,72 |
|
8178086 |
Heat shock 70 kDa protein 1A /// heat shock 70 kDa protein 1B |
HSPA1A /// HSPA1B |
-1,78 |
3,43 |
|
8179324 | ||||
|
8118314 | ||||
|
8179322 | ||||
|
8118310 | ||||
|
8166585 |
Hypothetical locus FLJ32742 |
FLJ32742 |
1,77 |
3,41 |
|
7920873 |
Small nucleolar RNA, H/ACA box 42 |
SNORA42 |
1,74 |
3,35 |
|
7899436 |
Sestrin 2 |
SESN2 |
1,66 |
3,17 |
|
8139737 |
Phosphoserine phosphatase |
PSPH |
1,66 |
3,17 |
|
8060344 |
Tribbles homolog 3 (Drosophila) |
TRIB3 |
1,62 |
3,08 |
|
8122724 |
UL16 binding protein 1 |
ULBP1 |
1,61 |
3,06 |
|
8143341 |
Jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) |
JHDM1D |
1,61 |
3,06 |
| 8084219 | Kelch-like 24 (Drosophila) | KLHL24 | 1,59 | 3,03 |
Presented genes are involved in cellular amino-acid biosynthesis, stress response, carboxylic and organic acid biosynthetic process, amine biosynthetic process. Gene clustering based on Gene Ontology identified two clusters: apoptosis and ion binding.