Table 3.
Differentially transcribed host genes up or down-regulated by >3-fold at 24 h after C. trachomatis persistent infection of CNDT-2 cells compared to non-infected
| Affymetrix ID | Gene name | Gene symbol | Log2 fold change | Absolute fold change |
|---|---|---|---|---|
|
8102800 |
Solute carrier family 7, (cationic amino acid transporter, y + system) member 11 |
SLC7A11 |
3,77 |
13,56 |
|
7982868 |
ChaC, cation transport regulator homolog 1 (E. coli) |
CHAC1 |
3,28 |
9,71 |
|
7928308 |
DNA-damage-inducible transcript 4 |
DDIT4 |
2,47 |
5,55 |
|
8146934 |
Lymphocyte antigen 96 |
LY96 |
2,09 |
4,26 |
|
8154381 |
Chromosome 9 open reading frame 150 |
C9orf150 |
1,96 |
3,89 |
|
8143341 |
Jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) |
JHDM1D |
1,93 |
3,81 |
|
8122724 |
UL16 binding protein 1 |
ULBP1 |
1,85 |
3,61 |
|
8174361 |
TSC22 domain family, member 3 |
TSC22D3 |
1,75 |
3,36 |
|
8122202 |
v-myb myeloblastosis viral oncogene homolog (avian) |
MYB |
-1,73 |
3,31 |
|
7912157 |
ERBB receptor feedback inhibitor 1 |
ERRFI1 |
1,71 |
3,27 |
|
8156043 |
Phosphoserine aminotransferase 1 |
PSAT1 |
1,71 |
3,27 |
|
8139737 |
Phosphoserine phosphatase |
PSPH |
1,70 |
3,26 |
|
7899436 |
Sestrin 2 |
SESN2 |
1,65 |
3,14 |
|
7902290 |
Cystathionase (cystathionine gamma-lyase) |
CTH |
1,59 |
3,02 |
| 8049542 | Leucine rich repeat (in FLII) interacting protein 1 | LRRFIP1 | 1,59 | 3,00 |
Gene clustering based on Gene Ontology identified five clusters: amine biosynthesis, apoptosis, transcription regulator activity, intrinsic to membrane and ion binding.