Table 1a.
Clinical characteristics | Reinfarction (N=50) | No Reinfarction (N=253) | p-value | ||
---|---|---|---|---|---|
n | % (mean ± sd) median{IQR} | n | % (mean ± sd) median{IQR} | ||
Age (Years) | 50 | (59.9±12.9) | 253 | (64.8±11) | 0.005 |
| |||||
Sex | 0.90 | ||||
Male | 36 | 72.0 | 180 | 71.1 | |
Female | 14 | 28.0 | 73 | 28.9 | |
| |||||
Prior History of | |||||
Angina | 16 | 32.0 | 81 | 32.0 | 1.00 |
MI | 11 | 22.0 | 31 | 12.3 | 0.07 |
Cerebrovascular Disease | 3 | 6.0 | 24 | 9.5 | 0.43 |
Peripheral Vessel Disease | 4 | 8.0 | 22 | 8.7 | 0.87 |
Congestive Heart Failure | 8 | 16.0 | 18 | 7.1 | 0.04 |
PCI | 7 | 14.0 | 20 | 7.9 | 0.17 |
CABG | 1 | 2.0 | 2 | 0.8 | 0.43 |
Diabetes | 14 | 28.0 | 84 | 33.2 | 0.47 |
Hypertension | 23 | 46.0 | 155 | 61.3 | 0.05 |
| |||||
Current Smoker | 19 | 38.0 | 83 | 32.8 | 0.48 |
| |||||
CHF at Baseline | 27 | 54.0 | 126 | 49.8 | 0.59 |
Highest Killip Class II–IV During Index MI | 15 | 30.6 | 91 | 36.0 | 0.47 |
Highest NYHA Classification II–IV | 17 | 34.0 | 85 | 33.6 | 0.96 |
| |||||
ECG with index MI | |||||
ST-segment Elevation | 36 | 72.0 | 178 | 71.5 | 0.94 |
New Q-Waves | 20 | 40.0 | 169 | 66.8 | <0.001 |
ST-segment elevation /new Q waves/R wave loss | 40 | 80.0 | 218 | 86.2 | 0.26 |
| |||||
Rales Present | 9 | 18.0 | 41 | 16.2 | 0.76 |
Collateral Vessels Present | 42 | 84.0 | 208 | 82.5 | 0.80 |
Ejection Fraction | 49 | (43.6±12.6) | 250 | (43.1±13) | 0.82 |
Systolic Blood Pressure | 50 | (118.3±22) | 253 | (122.6±20.2) | 0.18 |
Diastolic Blood Pressure | 50 | (69±11.8) | 253 | (72.7±12) | 0.05 |
BMI | 50 | (28.9±6.8) | 253 | (29.1±6.3) | 0.80 |
Glomerular filtration*rate (ml/min/1.72m^2) | 50 | (79.4±27.4) | 248 | (73±22.8) | 0.08 |
Fasting Glucose (mg/dl) | 48 | (133±54.8) | 234 | (127.2±47.8) | 0.46 |
| |||||
Interval between MI and randomization (days) | 50 | 7{4–13} | 253 | 8{4–15} | 0.31 |
Infarct-related Artery | 0.40 | ||||
LAD | 23 | 46 | 110 | 43.5 | |
LCX | 11 | 22 | 40 | 15.8 | |
RCA | 16 | 32 | 103 | 40.7 | |
Ischemia in Infarct-Related Artery Territory | 2 | 28.6 | 21 | 44.7 | 0.42 |
| |||||
Thrombolytic Therapy During 1st 24 hours | 12 | 24.0 | 48 | 19.0 | 0.42 |
PCI: Percutaneous coronary intervention, CABG: Coronary artery bypass graft, CHF: Congestive heart failure, NYHA: New York Heart Association, ECG: Electrocardiogramm, MI: Myocardial infarction, BMI: Body mass index, LAD: Left anterior descending coronary artery, LCX: Left circumflex coronary artery, RCA: Right coronary artery.