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Proliferation of MG63 human osteosarcoma cells in response to growth in extract from (A, B, C) bone cement and (D, E, F) OCA after (A, D) 24, (B, E) 48, and (C, F) 72 h (average ± SEM, n = 4). Proliferation of cells in the positive controls, Cu and Loctite®, was significantly different from all treatment groups, although significance is not indicated on the figures.
